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Aciclovir; Famvir; Valtrex;. Red blood cells will burst every 48 to 72 hours. Every time this happens, you'll experience an attack of chills, fever and sweating.. (aciclovir) by HSV drug. The cytopathic effect (CPE) caused by HSVusually develops 24-72 hours after inoculation, and is characterized by enlarged, refractile,.

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